| # | Name | Took Office | Left Office | Party | |
|---|---|---|---|---|---|
| 1 | Gerald Strickland, 1st time | 1921 | 1927 | Constitutional Party | |
| 2 | Ugo Pasquale Mifsud | 1927 | 1932 | Nationalist Party | |
| Gerald Strickland, 2nd time | 1932 | 1933 | Constitutional Party | ||
| Office Abolished | |||||
| 3 | Enrico Mizzi | 1947 | 1950 | Nationalist Party | |
| 4 | Dom Mintoff, 1st time | 1950 | 1955 | Malta Labour Party | |
| 5 | Giorgio Borg Olivier, 1st time | 1955 | 1958 | Nationalist Party | |
| Office Abolished | |||||
| Dom Mintoff, 2nd time | 1962 | 1971 | Malta Labour Party | ||
| Giorgio Borg Olivier, 2nd time | 1971 | 1977 | Nationalist Party | ||
| 6 | Eddie Fenech Adami, 1st time | 1977 | 1987 | Nationalist Party | |
| 7 | Karmenu Mifsud Bonnici | 1987 | 1992 | Malta Labour Party | |
| 8 | Alfred Sant, 1st time | 1992 | 1996 | Malta Labour Party | |
| Eddie Fenech Adami, 2nd time | 1996 | 1998 | Nationalist Party | ||
| Alfred Sant, 2nd time | 1998 | 2008 | Malta Labour Party | ||
| 9 | Charles Mangion | 2008 | 2008 | Malta Labour Party | |
| 10 | Joseph Muscat | 2008 | Present | Labour Party | |